In this study the authors observe that in indolent ulcers, placental dressing seems to free the lesion from infection and then procedures adequate granulation tissue formation and healing, enough to facilitate, if necessary, skin grafting. Placental treatment was found to be very effective, inexpensive and freely available when compared to any other drug therapy. Like amniotic membrane, placental dressing offers several advantages a=over many antibiotics and chemotherapeutic agents as in antibacterial activity vascularisation of wound environment and wound healing. Placental treatment was devoid of side-effects and graft rejection.
Placental treatment of ulcers in this study was found to be enhancing the humoral immune mechanism of the patient by increasing the immunoglobulin level and did not act as an irritant. IgM, specific for bacterial toxin increased considerably. IgG and IgM