Abstract: Wound infections and dehiscence is a common complication after surgical procedures. Particularly so in institutions with patient overload. Human placenta has been used as biological dressing to trat various types of wounds and ulcers. Hence, this study was done with Aim: to compare the efficacy of topical application of purified extract of human placenta (Placentrex) versus povidone iodine for their wound healing potential in surgical wounds.
Materials and Methods: This was an open comparative randomized study comprising 82 patients above 18 years of age undergoing clean surgeries. Enrolled patients were randomized as per the PC generated randomized chart (Rando 1.2, 2004) to receive either topical application of human placenta purified extract (PE) on the surgical wound or topical application of Povidone Iodine (PI) Ointment on the surgery, on days 3, 7 and 10, if required. Assessment of surgical wound was done