Gyn/Obs

EVALUATION OF PLACENTREX IN
PELVIC INFLAMMATORY DISEASE


Ref : Prof V L Bhargava, Department of Gynaecology & Obstetrics, AIIMS, New Delhi

Prof P N Sen, Department of Gynaecology & Obstetrics, National Medical College, Calcutta


 


EVALUATION OF PLACENTREX IN PELVIC INFLAMMATORY DISEASE (Data on File)

  It is a multicentric trial conducted at the above centres and the results were summarized as follows :

  PID is a common condition with considerable degree of physical and emotional morbidity. 50 patients were treated with 2ml IM Placentrex x 21 days and 50 on conventional anti-inflammatory drug therapy. Patients were followed up for a period   of four months after completion of protocol therapy.

  The number of patients reporting improvement in presenting symptoms of abdominal pain, dysmenorrhoea etc. was   statistically significant in the PLACENTREX group. Abdominal tenderness disappeared in statistically significant number of   patients in the PLACENTREX group.


  There were statistically more number of patients in the Placentrex group in whom excellent to good response was seen at   the end of four months after completion of protocol therapy.

  It can be observed that IM Placentrex is useful addition to the therapeutic armamentarium in the management of patients   with pelvic inflammatory disease. Its therapeutic effect persists for a period of at least four months after completion of 21   days therapy as per the present protocol. IM Placentrex is well accepted and tolerated by the patients without any side   effects.

 

Abdominal Pain:

Control
(n-= 50)
Initial
Final
Sig.
Absent
0
19
N.S.
Same

 

17
N.S.
Increased

 

6

 

Reduced

 

8

 

Placentrex
(n = 50)

 

 

 

Absent

 

30
P<0.01
Same

 

6

 

Increased

 

3
 
Reduced

 

11
P<0.05
Significance

 

 

P<0.05 for Px

Abdominal Tenderness:


Control
(n-= 50)
Initial
Final
Sig.
Absent

 

20
N.S.
Same

 

10
N.S.
Increased

 

8

 

Reduced

 

12

 

Placentrex
(n = 50)

 

 

 

Absent

 

39
P<0.01
Same

 

6

 

Increased

 

0

 

Reduced

 

5
P<0.05
Significance

 

 

P<0.05 for Px

Dysmenorrhoea:


Control
(n-= 50)
Initial
Final
Sig.
Absent

 

22
N.S.
Same

 

28
N.S.
Increased

 

0

 

Reduced

 

0

 

Placentrex
(n = 50)

 

 

 

Absent

 

37
P<0.01
Same

 

6

 

Increased

 

0

 

Reduced

 

7

 

Significance

 

 

P<0.05 for Px


Final evaluation:


 

control
placentrex
excellent
9
13
good
13
30
poor
28
17

 

 

 

significance

 

P<0.01 for placentrex


 THANK YOU